BIOCHEMICAL STUDIES ON REGENERATING LIVER
نویسندگان
چکیده
منابع مشابه
Biochemical studies on regenerating liver.
Regenerating liver of the rat has long been recognized as a source of relatively abundant quantities of homogeneous rapidly growing tissue. Following the removal of the two largest lobes of the liver, the remaining ones, constituting about one-third of the total, enlarge to the size of the original liver in the span of a few days. The work of Higgins and Anderson (l), Brues et al. (2), and othe...
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The basic morphological properties of liver cells are defined in the form of a morphometric model to permit integrated quantitative characterization of functionally important parameters. Stereologic methods which allow efficient and reliable quantitative evaluation of sectioned liver tissue are presented. Material, obtained by a rigorous three-stage sampling procedure from five normal rat liver...
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The effects of continuous administration of cortisone on the metabolism of regenerating rat liver have been studied. Whereas the restoration of the weight of the liver after partial hepatectomy was not markedly affected by cortisone, the multiplication of cells was reduced to a significant degree after the first 2 days of regeneration. Liver restoration in terms of nucleic acids was similarly i...
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utilization patterns of hamsters and rats bearing human neoplasms. These studies showed that, in sofar as the synthesis of the purine moiety of their nucleic acids is concerned, these tumors possess distinctive characteristics as compared with the host tissues. In the synthesis of the nucleic acids, the neoplastic tissue used guanine and hypoxan thine inefficiently as compared with the host, bu...
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In this report, the changes in the sedimentation character istics of the E. coli enzyme in the presence of nucleotides are confirmed. However, no alterations in the sedimentation constant were noted with the enzyme , which was partially purified from regenerating rat liver. The latter enzyme also exhibited a markedly different mobility in an electrophoretic field than E. coli TdR kinase. labora...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1948
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)35577-7